SUPERCRITICAL FLUID EXTRACTION DEFENSE METABOLITES APIS MELLIFERA BIOCATALYSIS RED PROPOLIS BRAZILIAN PROPOLIS CHARCONE ANTIOXIDANT ACTIVITY BOX–BEHNKENDESIGN ISOFLAVONOÏDES PLANTS RESIN ANTIMICROBIAL ACTIVITY BIOLOGICAL ACTIVITY GALACTOMANNAN REGIOSELECTIVE METHYLATION BIOFILMS GENISTIN DALBERGIA ECASTOPHYLLUM GENISTEIN OLIGOSACCHARIDES CANDIDA CANDIDIASIS NATURAL PRODUCTS CANDIDOSE PHENYLPROPANOID PATHWAY BIOACTIVE COMPOUNDS DAIDZEIN SOY FLOUR