GLP-1 ENDOGENOUS GLUCOSE PRODUCTION DIABETES SITAGLIPTIN DPP-IV INHIBITORS ENERGY EXPENDITURE OBESITY INSULIN RESISTANCE METABOLIC PREDICTORS DYSGLICEMIA PROGRESSION FAMILY HISTORY STAUB TRAUGOTT EFFECT GLUCOSE TOLERANCE ORAL GLUCOSE TOLERANCE TEST INSULIN SECRETION GIP INCRETIN EFFECT MIXED MEAL GLUCAGON GASTRIC BYPASS EUGLYCEMIC INSULIN CLAMP BILIOPANCREATIC DIVERSION URINARY GLUCOSE EXCRETION INSULIN SENSIBILITY EMPAGLIFLOZIN MATHEMATICAL MODEL BARIATRIC SURGERY ISOGLYCAEMIC PROTOCOL ACIPIMOX BRANCHED-CHAIN AMINOACIDS INSULIN SENSITIVITY GLUCOSE TOLERANCE TEST DIABETES MELLITUS TIPO 2 INTRAVENOUS ISOGLYCEMIC TEST CLAMP EUGLICÊMICO HIPERINSULINÊMICO ILEAL INTERPOSITION NEFA RESISTÊNCIA À INSULINA ADIPONECTINA EMAGRECIMENTO